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Even if every human on earth had their own pet since dogs were first domesticated ten or twenty thousand years ago, their ancestors were facing the stress of migrating into new and unfamiliar environments for several hundred thousand years prior to that.
Certainly. But we still cannot say that should mean every beneficial mutation for their lives was likely to be adopted. Like I said earlier, the majority of possibly good things are left on the table, even when drawbacks are not considered.
Including drawbacks muddies it up even further, we can look at how cardiovascular shock occurs and how the particular traits that create it were a bit of a double edged sword.