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I agree that it is ridiculous to claim that it is impossible and outright dismiss the idea. Nobody can say it doesn't come from there and proving a negative is impossible. However there are a number of reasons which make the Wuhan thing a lot less suspicious than it seems at first glance.
Wuhan is the 7th largest Chinese city, and is among the most prolific research cities in China, so of course you'd have a lot of virology labs there and that would be the most probable location for coronavirus-related research. Remember that coronaviruses were kind of a hot topic in Asia after the SARS epidemic in the early 2000s.
Respiratory viruses, obviously, thrive in high-density population centers, so it would stand to reason that a 13 million inhabitants agglomeration would be at the center of this kind of thing.
To put this into perspective : if COVID had appeared in France, near some podunk town of 30K inhabitants that just happens to have a coronavirus-related lab - OK that would be super suspicious. But most likely it would have originated near Paris which is the largest population center in the whole region. Well that's also where the Pasteur Institute is, and the Pasteur Institute being the largest virology research center in the country is the most likely place where you'd find coronavirus research. All of a sudden that would be a lot less shady.