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a conditioned response to stimuli that go against your attachments. Positive and negative are just perceptions colored by the mind based on attachments like survival.
I have to be clear that this is more a direct realisation of truth than something you actively do.
You can use neurobiology to prove it and meditation to see it for yourselves. All thoughts, decisions etc happen unconsciously and then the consciousness becomes aware of it—like a spectator.
So it's simple. There's no need to play a game or to play it well or for longer. Or there's a need to to achieve anything. You are already there standing still in the bliss of the moment.
The brain adjusts back to normal levels of happiness after new circumstances or chemistry.
"perfection" is an imaginary concept. What do you mean by a perfect life?
Then perhaps there was a misunderstanding. I assumed you meant actively letting go of attachment. Because I agree, doing so mentally allows for a certain numbing of sensations that are experienced. Our views on that might be very similar, but we just word them differently.
And when I mentioned a "perfect life" I was refering to a subjective perfection. Everyting going just how you want it to. And obviously, the drug dosage in the theoretical scenario would be adjusted accordingly to the body/brain developing resistance.
A "small" note/question. If happiness is just circumstances or chemistry, then so is suffering. In that case we don't need to let go of attachment, just the circumstances or chemistry that cause emotions in the first place. Would you agree with that statement? Although the complete removal of emotions could cause complete detachment from reality in a human being, so I guess it goes back around to attachment again.