I lived in the deep south my whole life. Almost everyone I knew was conservative. Parents, siblings, a grandparent, friends, neighbors, colleagues and almost everyone else in my life was conservative.
After I retired and Trump won again, I decided to disown them all. I politely said goodbye to everyone, explaining I will be difficult to contact for a while, but not to worry. I then moved 1800 miles away to a nice blue part of the country. It was physically and financially very difficult. I changed my phone number and email and gave no one any way to contact me, except the few non-conservative friends I have. I have no plans to ever speak with any of them ever again.
It's been almost 2 years now. I couldn't be happier. My stress is significantly lower without conservatives in it. I now wear my politics on my sleeve, which has resulted in a large number of new, high quality friends. I no longer feel any desire to drink and truly believe my depression is gone. I really do enjoy life right now, despite my concerns that civil war and genocide are upon us.
Disowning conservatives is the absolute best thing I have ever done to improve my quality of life. I highly recommend it.