this post was submitted on 15 May 2026
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[–] Vanth@reddthat.com 45 points 1 week ago

There will be outbreaks of other corona viruses in the future. I wonder if this medicine will be effective against them or at least will be a baseline from which adjustments can be more quickly made to be effective against a different corona virus. This is one of the most positive news stories I've seen today.

[–] BedSharkPal@lemmy.ca 16 points 1 week ago (3 children)

Just give me a nasal vaccine please

[–] Buffalox@lemmy.world 7 points 1 week ago (1 children)

That would be awesome, I think that would be about as benign as injection, taking it through mucous membrane bypasses the digestive system, which is generally way more problematic.

[–] Mouselemming@sh.itjust.works 4 points 1 week ago (1 children)

And seems to me it ought to be extra effective if the immune reaction is centered near the usual source of the infection. Unless you have a bad reaction to the vaccine of course

[–] BedSharkPal@lemmy.ca 1 points 1 week ago (1 children)

Animal studies show it is way more effective. You want to activate and train the immune cells that will first be exposed to the virus. Traditional needle base vaccines help deal with the virus once it's already in your body. Great for managing the infection and ensuring it's scope is limited.

A nasal vaccine could stop people from being infected at all. Which is what they saw in animal studies so far.

[–] Drusas@fedia.io 2 points 1 week ago

But important to know that the nasal vaccine (for flu) uses live virus, making it unsuitable for anyone with an immune deficiency.

[–] corsicanguppy@lemmy.ca 5 points 1 week ago

I got like 9 or 11 injections in one 30-sec army jabfest in 91. I still don't like needles, but I'll roll up my arm or drop trou for something beneficial with no complaint. The alternative is always worse.

[–] fonix232@fedia.io 2 points 1 week ago (5 children)

Imagine if your annual vaccination was a simple nose spray.

[–] jtrek@startrek.website 2 points 1 week ago (2 children)

That doesn't sound much different than a traditional vaccine, unless you can self administer it

[–] HubertManne@piefed.social 3 points 1 week ago (1 children)

its massive for needlephobes.

[–] jtrek@startrek.website 0 points 1 week ago (1 children)

Probably get more return on resources investing in therapy to address phobias, in that case.

[–] HubertManne@piefed.social 1 points 1 week ago (1 children)

you mean society or the individual?

[–] jtrek@startrek.website 1 points 1 week ago (1 children)
[–] HubertManne@piefed.social 3 points 1 week ago

I mean individual wise I think you just don't get it and maybe mental health in general. TLDR - just get over it or go find some therapy and bingo bango boom. done. Society wise having resources would at least make it more possible for people who try. Honestly though its likely cheaper and easier to just have a nasal spray option but its holistically better for the individual to just not have phobias or really any mental health problems.

[–] fonix232@fedia.io 1 points 1 week ago

It does when you can't stand needles. Also the convenience of being able to pick it up in a corner store vs having to go to a doctor.

[–] Zorcron@lemmy.zip 1 points 1 week ago

There’s been a nasal flu vaccine for a while but it’s not as effective as the intramuscular ones.

[–] Drusas@fedia.io 1 points 1 week ago

Some of us really hate spraying stuff up our noses. I'll keep my injection, thanks.

[–] homura1650@lemmy.world 1 points 1 week ago

We've had nasal flu vaccines for decades.

[–] tobebannedbygaymods@lemmy.zip 0 points 1 week ago

People take Annual Vaccines ?

[–] HubertManne@piefed.social 14 points 1 week ago

Ensitrelvir works by blocking a key enzyme that the virus relies on to make new copies of itself. This enzyme is also targeted by Paxlovid. But unlike Paxlovid, ensitrelvir was shown to significantly reduce the risk of developing COVID-19 symptoms compared to a placebo among those who had been exposed to the virus.

[–] Aqarius@lemmy.world 9 points 1 week ago (2 children)

...Wait, wouldn't that literally make it a cure for the common cold?

[–] Rekhyt@lemmy.world 12 points 1 week ago

I think it's a cure for the uncommon cold.

[–] vxx@lemmy.world 2 points 1 week ago

I don't think so. The common cold is caused by about 200 different viruses or variants of the rhinovirus. Incubation is also very low with 24-72 hours, so you would have to basically take it every time someone sneezes around you.

[–] tobebannedbygaymods@lemmy.zip 2 points 1 week ago (1 children)
[–] Zorcron@lemmy.zip 13 points 1 week ago

No, this doesn’t prime your immune system; it works directly against the virus, so you need the drug in your system actively to benefit from the effects.

[–] Lucidlethargy@sh.itjust.works 2 points 1 week ago

Just. In. Time.