this post was submitted on 25 Mar 2025
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[–] avidamoeba@lemmy.ca 28 points 1 month ago* (last edited 1 month ago) (24 children)

OK, so if I understand this correctly, they don't train the immune system to target these sugars, since they're used by human cells. Instead, they remove them during the vaccine administration so the immune system can train on the bare spike protein. Cool. Now how would this help when new virus copies come in with sugar-coated proteins, some time after the sugar stripping agent is gone from the system?

[–] AlolanYoda@mander.xyz 10 points 1 month ago* (last edited 1 month ago) (4 children)

Yeah I also don't understand this part. Can the antibodies targeting the bare spike protein attach to it despite the presence of the sugars? Or are there a few spike proteins in the virus which do not have the sugars, not enough to effectively develop antibodies but enough for already existing antibodies to attach to?

I may have missed it in the article, I'm not in life sciences so I don't have all the prerequisite knowledge for this

Edit: this came out sounding super negative, I'm actually super excited about this development and all I want is to understand a bit better how it works

[–] avidamoeba@lemmy.ca 4 points 1 month ago

Yes same, I see they've gotten a positive result so I assume there's a process, I just don't understand it.

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